STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFR69620.1O-acetylhomoserine (thiol)-lyase. (423 aa)    
Predicted Functional Partners:
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
 
 0.960
SFR75043.1
5-methyltetrahydrofolate--homocysteine methyltransferase.
  
 
 0.940
SFR89209.1
Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.910
SFR78038.1
Homoserine dehydrogenase.
  
 
 0.899
SFR74996.1
O-acetylhomoserine (thiol)-lyase.
  
  
 
0.889
SFR65402.1
Threonine dehydratase.
   
 
  0.884
SFR64519.1
S-ribosylhomocysteine lyase /quorum-sensing autoinducer 2 (AI-2) synthesis protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
 0.883
SFR64005.1
Cystathione beta-lyase.
 
 
 0.871
SFR63998.1
Cystathionine gamma-synthase.
 
 
0.853
SFR63586.1
Methionine synthase II (cobalamin-independent).
  
 
 0.747
Your Current Organism:
Clostridium aminophilum
NCBI taxonomy Id: 1526
Other names: ATCC 49906, DSM 10710, [. aminophilum, [Clostridium] aminophilum, strain F
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