STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALT00257.1A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (352 aa)    
Predicted Functional Partners:
ALS96980.1
Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
 
  
 0.973
sfsA
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SfsA family.
 
    0.930
ALS98597.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.853
ALS98791.1
Coenzyme A pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.603
ALS96981.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.550
ALT00149.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.545
trmB
tRNA (guanine-N7)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.533
ALS98254.1
Cysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.527
rsmC
16S rRNA methyltransferase; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.
       0.506
birA
biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
  
 0.500
Your Current Organism:
Lacimicrobium alkaliphilum
NCBI taxonomy Id: 1526571
Other names: Alteromonadaceae bacterium X13M-12, CGMCC 1.12923, KCTC 42674, L. alkaliphilum, Lacimicrobium alkaliphilum Zhong et al. 2016, strain X13M-12
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