STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sepFCell division inhibitor SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (189 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.987
SFN86711.1
Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.957
SFN86636.1
Cell division initiation protein.
  
  
 0.932
SFN86651.1
RNA-binding protein YlmH, contains S4-like domain.
 
  
 0.922
SFO42519.1
Cell division protein FtsA.
  
 
 0.836
codY
Transcriptional pleiotropic repressor; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
   
    0.716
SFN86673.1
YGGT family protein.
       0.705
cinA
Nicotinamide-nucleotide amidase; Belongs to the CinA family.
 
   
 0.700
SFN86730.1
Hypothetical protein.
       0.690
SFN92255.1
Uncharacterized protein, UPF0297 family; Belongs to the UPF0297 family.
  
  
 0.638
Your Current Organism:
Anaerocolumna aminovalerica
NCBI taxonomy Id: 1527
Other names: A. aminovalerica, ATCC 13725, CIP 104304, Clostridium aminovalericum, JCM 11016
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