node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFO13987.1 | SFO64740.1 | SAMN04489757_110100 | SAMN04489757_15511 | Phosphoribosylformylglycinamidine synthase. | CBS domain-containing protein. | 0.482 |
SFO13987.1 | apt | SAMN04489757_110100 | SAMN04489757_102138 | Phosphoribosylformylglycinamidine synthase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.859 |
SFO13987.1 | argS | SAMN04489757_110100 | SAMN04489757_10360 | Phosphoribosylformylglycinamidine synthase. | arginyl-tRNA synthetase. | 0.668 |
SFO13987.1 | argS-2 | SAMN04489757_110100 | SAMN04489757_11784 | Phosphoribosylformylglycinamidine synthase. | arginyl-tRNA synthetase. | 0.668 |
SFO13987.1 | guaA | SAMN04489757_110100 | SAMN04489757_106135 | Phosphoribosylformylglycinamidine synthase. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.997 |
SFO13987.1 | guaB | SAMN04489757_110100 | SAMN04489757_10748 | Phosphoribosylformylglycinamidine synthase. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.960 |
SFO13987.1 | pyrG | SAMN04489757_110100 | SAMN04489757_10674 | Phosphoribosylformylglycinamidine synthase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.765 |
SFO13987.1 | xpt | SAMN04489757_110100 | SAMN04489757_11662 | Phosphoribosylformylglycinamidine synthase. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.859 |
SFO64740.1 | SFO13987.1 | SAMN04489757_15511 | SAMN04489757_110100 | CBS domain-containing protein. | Phosphoribosylformylglycinamidine synthase. | 0.482 |
SFO64740.1 | apt | SAMN04489757_15511 | SAMN04489757_102138 | CBS domain-containing protein. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.476 |
SFO64740.1 | guaA | SAMN04489757_15511 | SAMN04489757_106135 | CBS domain-containing protein. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.992 |
SFO64740.1 | guaB | SAMN04489757_15511 | SAMN04489757_10748 | CBS domain-containing protein. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.866 |
SFO64740.1 | xpt | SAMN04489757_15511 | SAMN04489757_11662 | CBS domain-containing protein. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.476 |
apt | SFO13987.1 | SAMN04489757_102138 | SAMN04489757_110100 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylformylglycinamidine synthase. | 0.859 |
apt | SFO64740.1 | SAMN04489757_102138 | SAMN04489757_15511 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | CBS domain-containing protein. | 0.476 |
apt | guaA | SAMN04489757_102138 | SAMN04489757_106135 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.992 |
apt | guaB | SAMN04489757_102138 | SAMN04489757_10748 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.942 |
apt | pyrG | SAMN04489757_102138 | SAMN04489757_10674 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.634 |
apt | xpt | SAMN04489757_102138 | SAMN04489757_11662 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.936 |
argS | SFO13987.1 | SAMN04489757_10360 | SAMN04489757_110100 | arginyl-tRNA synthetase. | Phosphoribosylformylglycinamidine synthase. | 0.668 |