STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFO40264.1Hypothetical protein. (147 aa)    
Predicted Functional Partners:
SFO40251.1
Anti-sigma regulatory factor (Ser/Thr protein kinase).
   
 0.995
SFO40241.1
Iron only hydrogenase large subunit, C-terminal domain.
 
   
 0.921
SFO40291.1
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
   
 0.910
SFO40230.1
Hypothetical protein.
 
  
 0.907
SFO40219.1
Hypothetical protein.
 
     0.897
SFO40303.1
NAD(P)-dependent iron-only hydrogenase iron-sulfur protein.
 
   
 0.883
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.825
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
    
  0.787
tilS
Hypoxanthine phosphoribosyltransferase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
     
  0.754
SFO40315.1
NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein.
 
   
 0.683
Your Current Organism:
Anaerocolumna aminovalerica
NCBI taxonomy Id: 1527
Other names: A. aminovalerica, ATCC 13725, CIP 104304, Clostridium aminovalericum, JCM 11016
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