node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFO45608.1 | rplA | SAMN04489757_1281 | SAMN04489757_12810 | Translation elongation factor 1A (EF-1A/EF-Tu). | Large subunit ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.983 |
SFO45608.1 | rplB | SAMN04489757_1281 | SAMN04489757_13712 | Translation elongation factor 1A (EF-1A/EF-Tu). | LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.987 |
SFO45608.1 | rplD | SAMN04489757_1281 | SAMN04489757_13710 | Translation elongation factor 1A (EF-1A/EF-Tu). | Large subunit ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.983 |
SFO45608.1 | rplK | SAMN04489757_1281 | SAMN04489757_12811 | Translation elongation factor 1A (EF-1A/EF-Tu). | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.992 |
SFO45608.1 | rplP | SAMN04489757_1281 | SAMN04489757_13716 | Translation elongation factor 1A (EF-1A/EF-Tu). | Large subunit ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.983 |
SFO45608.1 | rpsG | SAMN04489757_1281 | SAMN04489757_1283 | Translation elongation factor 1A (EF-1A/EF-Tu). | Small subunit ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.990 |
SFO45608.1 | rpsJ | SAMN04489757_1281 | SAMN04489757_1378 | Translation elongation factor 1A (EF-1A/EF-Tu). | SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.988 |
SFO45608.1 | rpsL | SAMN04489757_1281 | SAMN04489757_1284 | Translation elongation factor 1A (EF-1A/EF-Tu). | SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.990 |
SFO45608.1 | rpsM | SAMN04489757_1281 | SAMN04489757_13734 | Translation elongation factor 1A (EF-1A/EF-Tu). | Small subunit ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. | 0.985 |
SFO45608.1 | tsf | SAMN04489757_1281 | SAMN04489757_14331 | Translation elongation factor 1A (EF-1A/EF-Tu). | Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.996 |
rplA | SFO45608.1 | SAMN04489757_12810 | SAMN04489757_1281 | Large subunit ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Translation elongation factor 1A (EF-1A/EF-Tu). | 0.983 |
rplA | rplB | SAMN04489757_12810 | SAMN04489757_13712 | Large subunit ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.997 |
rplA | rplD | SAMN04489757_12810 | SAMN04489757_13710 | Large subunit ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Large subunit ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.999 |
rplA | rplK | SAMN04489757_12810 | SAMN04489757_12811 | Large subunit ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.999 |
rplA | rplP | SAMN04489757_12810 | SAMN04489757_13716 | Large subunit ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Large subunit ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.996 |
rplA | rpsG | SAMN04489757_12810 | SAMN04489757_1283 | Large subunit ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Small subunit ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.996 |
rplA | rpsJ | SAMN04489757_12810 | SAMN04489757_1378 | Large subunit ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.997 |
rplA | rpsL | SAMN04489757_12810 | SAMN04489757_1284 | Large subunit ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.996 |
rplA | rpsM | SAMN04489757_12810 | SAMN04489757_13734 | Large subunit ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Small subunit ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. | 0.995 |
rplA | tsf | SAMN04489757_12810 | SAMN04489757_14331 | Large subunit ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.969 |