STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFO61228.1DNA (cytosine-5)-methyltransferase 1. (356 aa)    
Predicted Functional Partners:
SFO61219.1
AAA domain (dynein-related subfamily).
 
   
 0.872
SFO61241.1
DNA (cytosine-5)-methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
 
    
0.811
SFO61203.1
LlaJI restriction endonuclease.
     
 0.772
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.722
speD
S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
  
  
  0.706
SFO08543.1
Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
  0.667
SFO61256.1
DNA binding domain-containing protein, excisionase family.
       0.611
SFO62415.1
Putative AdoMet-dependent methyltransferase.
    
  0.547
SFO61189.1
Diguanylate cyclase (GGDEF) domain-containing protein.
       0.485
SFO59576.1
Nucleoside phosphorylase.
    
  0.450
Your Current Organism:
Anaerocolumna aminovalerica
NCBI taxonomy Id: 1527
Other names: A. aminovalerica, ATCC 13725, CIP 104304, Clostridium aminovalericum, JCM 11016
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