node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFO36650.1 | SFO36664.1 | SAMN04489757_12049 | SAMN04489757_12050 | Homocysteine S-methyltransferase. | 5-methyltetrahydrofolate--homocysteine methyltransferase. | 0.999 |
SFO36650.1 | SFO40799.1 | SAMN04489757_12049 | SAMN04489757_12356 | Homocysteine S-methyltransferase. | Manganese-dependent inorganic pyrophosphatase. | 0.422 |
SFO36650.1 | SFO64740.1 | SAMN04489757_12049 | SAMN04489757_15511 | Homocysteine S-methyltransferase. | CBS domain-containing protein. | 0.730 |
SFO36650.1 | guaA | SAMN04489757_12049 | SAMN04489757_106135 | Homocysteine S-methyltransferase. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.748 |
SFO36650.1 | guaB | SAMN04489757_12049 | SAMN04489757_10748 | Homocysteine S-methyltransferase. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.639 |
SFO36650.1 | tilS | SAMN04489757_12049 | SAMN04489757_15212 | Homocysteine S-methyltransferase. | Hypoxanthine phosphoribosyltransferase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.510 |
SFO36664.1 | SFO36650.1 | SAMN04489757_12050 | SAMN04489757_12049 | 5-methyltetrahydrofolate--homocysteine methyltransferase. | Homocysteine S-methyltransferase. | 0.999 |
SFO36664.1 | SFO64740.1 | SAMN04489757_12050 | SAMN04489757_15511 | 5-methyltetrahydrofolate--homocysteine methyltransferase. | CBS domain-containing protein. | 0.726 |
SFO36664.1 | guaA | SAMN04489757_12050 | SAMN04489757_106135 | 5-methyltetrahydrofolate--homocysteine methyltransferase. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.735 |
SFO36664.1 | guaB | SAMN04489757_12050 | SAMN04489757_10748 | 5-methyltetrahydrofolate--homocysteine methyltransferase. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.918 |
SFO36664.1 | tilS | SAMN04489757_12050 | SAMN04489757_15212 | 5-methyltetrahydrofolate--homocysteine methyltransferase. | Hypoxanthine phosphoribosyltransferase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.531 |
SFO40799.1 | SFO36650.1 | SAMN04489757_12356 | SAMN04489757_12049 | Manganese-dependent inorganic pyrophosphatase. | Homocysteine S-methyltransferase. | 0.422 |
SFO40799.1 | SFO64740.1 | SAMN04489757_12356 | SAMN04489757_15511 | Manganese-dependent inorganic pyrophosphatase. | CBS domain-containing protein. | 0.818 |
SFO40799.1 | atpC | SAMN04489757_12356 | SAMN04489757_101129 | Manganese-dependent inorganic pyrophosphatase. | F-type H+-transporting ATPase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.872 |
SFO40799.1 | atpF | SAMN04489757_12356 | SAMN04489757_101134 | Manganese-dependent inorganic pyrophosphatase. | ATP synthase F0 subcomplex B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. | 0.818 |
SFO40799.1 | guaA | SAMN04489757_12356 | SAMN04489757_106135 | Manganese-dependent inorganic pyrophosphatase. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.772 |
SFO40799.1 | guaB | SAMN04489757_12356 | SAMN04489757_10748 | Manganese-dependent inorganic pyrophosphatase. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.948 |
SFO40799.1 | purA | SAMN04489757_12356 | SAMN04489757_107115 | Manganese-dependent inorganic pyrophosphatase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.452 |
SFO40799.1 | tilS | SAMN04489757_12356 | SAMN04489757_15212 | Manganese-dependent inorganic pyrophosphatase. | Hypoxanthine phosphoribosyltransferase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.742 |
SFO41244.1 | SFO64740.1 | SAMN04489757_1244 | SAMN04489757_15511 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | CBS domain-containing protein. | 0.575 |