STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHF03452.1NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family. (261 aa)    
Predicted Functional Partners:
SHE58141.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
 0.944
SHE72149.1
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.912
accD
acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
 
 0.902
SHE72198.1
[acyl-carrier-protein] S-malonyltransferase.
 0.887
SHE46248.1
PTS system, D-glucosamine-specific IIC component.
     
 0.859
SHE85471.1
PTS system D-glucose-specific IIA component, Glc family /PTS system D-glucose-specific IIB component, Glc family /PTS system D-glucose-specific IIC component, Glc family.
     
 0.859
fabZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 0.839
SHE85530.1
Hypothetical protein.
    
 0.839
SHF13169.1
PTS system IIC component, Gat family.
  
 
  0.833
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.824
Your Current Organism:
Clostridium fallax
NCBI taxonomy Id: 1533
Other names: ATCC 19400, BCRC 14512, Bacillus fallax, C. fallax, CCRC 14512, CCRC:14512, CCUG 4853, DSM 2631, NCIMB 10634, NCTC 8380, VPI 5729, Vallorillus fallax
Server load: low (16%) [HD]