STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JP74_04265Riboflavin biosynthesis protein RibD; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.811
JP74_15685
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.747
JP74_01835
Riboflavin biosynthesis protein RibD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.725
JP74_08500
Deaminase/reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.707
JP74_19890
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.696
JP74_06075
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.575
JP74_18100
Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family.
     
 0.575
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
    
 0.573
JP74_01005
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.563
JP74_05935
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.534
Your Current Organism:
Devosia sp. 172E8
NCBI taxonomy Id: 1535287
Other names: D. sp. 17-2-E-8, Devosia sp. 17-2-E-8
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