node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KGJ88108.1 | KGJ88109.1 | ND16A_2661 | ND16A_2662 | KEGG: ilvG, acetolactate synthase 2 catalytic subunit. | Hypothetical protein; KEGG: ilvM, acetolactate synthase 2 regulatory subunit. | 0.805 |
KGJ88108.1 | KGJ98012.1 | ND16A_2661 | ND16A_0817 | KEGG: ilvG, acetolactate synthase 2 catalytic subunit. | D-amino-acid transaminase; KEGG: ilvE, branched-chain amino acid aminotransferase. | 0.528 |
KGJ88108.1 | KGJ99033.1 | ND16A_2661 | ND16A_0421 | KEGG: ilvG, acetolactate synthase 2 catalytic subunit. | KEGG: ilvI, acetolactate synthase III, large subunit, biosynthetic type. | 0.645 |
KGJ88108.1 | KGJ99034.1 | ND16A_2661 | ND16A_0422 | KEGG: ilvG, acetolactate synthase 2 catalytic subunit. | Hypothetical protein; KEGG: ilvH, acetolactate synthase 3 regulatory subunit. | 0.993 |
KGJ88108.1 | ilvA | ND16A_2661 | ND16A_2665 | KEGG: ilvG, acetolactate synthase 2 catalytic subunit. | Hypothetical protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.896 |
KGJ88108.1 | ilvC | ND16A_2661 | ND16A_2653 | KEGG: ilvG, acetolactate synthase 2 catalytic subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.959 |
KGJ88108.1 | ilvD-2 | ND16A_2661 | ND16A_2664 | KEGG: ilvG, acetolactate synthase 2 catalytic subunit. | KEGG: ilvD, dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.908 |
KGJ88108.1 | ilvE | ND16A_2661 | ND16A_2663 | KEGG: ilvG, acetolactate synthase 2 catalytic subunit. | Branched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.745 |
KGJ88108.1 | leuA | ND16A_2661 | ND16A_2180 | KEGG: ilvG, acetolactate synthase 2 catalytic subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.872 |
KGJ88108.1 | leuC | ND16A_2661 | ND16A_2178 | KEGG: ilvG, acetolactate synthase 2 catalytic subunit. | Hypothetical protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.796 |
KGJ88109.1 | KGJ88108.1 | ND16A_2662 | ND16A_2661 | Hypothetical protein; KEGG: ilvM, acetolactate synthase 2 regulatory subunit. | KEGG: ilvG, acetolactate synthase 2 catalytic subunit. | 0.805 |
KGJ88109.1 | KGJ98012.1 | ND16A_2662 | ND16A_0817 | Hypothetical protein; KEGG: ilvM, acetolactate synthase 2 regulatory subunit. | D-amino-acid transaminase; KEGG: ilvE, branched-chain amino acid aminotransferase. | 0.699 |
KGJ88109.1 | KGJ99033.1 | ND16A_2662 | ND16A_0421 | Hypothetical protein; KEGG: ilvM, acetolactate synthase 2 regulatory subunit. | KEGG: ilvI, acetolactate synthase III, large subunit, biosynthetic type. | 0.568 |
KGJ88109.1 | KGJ99034.1 | ND16A_2662 | ND16A_0422 | Hypothetical protein; KEGG: ilvM, acetolactate synthase 2 regulatory subunit. | Hypothetical protein; KEGG: ilvH, acetolactate synthase 3 regulatory subunit. | 0.674 |
KGJ88109.1 | ilvA | ND16A_2662 | ND16A_2665 | Hypothetical protein; KEGG: ilvM, acetolactate synthase 2 regulatory subunit. | Hypothetical protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.817 |
KGJ88109.1 | ilvC | ND16A_2662 | ND16A_2653 | Hypothetical protein; KEGG: ilvM, acetolactate synthase 2 regulatory subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.878 |
KGJ88109.1 | ilvD-2 | ND16A_2662 | ND16A_2664 | Hypothetical protein; KEGG: ilvM, acetolactate synthase 2 regulatory subunit. | KEGG: ilvD, dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.875 |
KGJ88109.1 | ilvE | ND16A_2662 | ND16A_2663 | Hypothetical protein; KEGG: ilvM, acetolactate synthase 2 regulatory subunit. | Branched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.883 |
KGJ88109.1 | leuA | ND16A_2662 | ND16A_2180 | Hypothetical protein; KEGG: ilvM, acetolactate synthase 2 regulatory subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.503 |
KGJ98012.1 | KGJ88108.1 | ND16A_0817 | ND16A_2661 | D-amino-acid transaminase; KEGG: ilvE, branched-chain amino acid aminotransferase. | KEGG: ilvG, acetolactate synthase 2 catalytic subunit. | 0.528 |