Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A0Q3HB71Protein kinase domain-containing protein. (494 aa)    
Predicted Functional Partners:
A0A0Q3SE71
Protein kinase domain-containing protein.
   
0.934
I1HQZ9_BRADI
Protein kinase domain-containing protein.
   
0.934
A0A0Q3HLH4
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 
 0.660
I1HD48_BRADI
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 
 0.660
I1HKY0_BRADI
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 
 0.660
A0A0Q3JPT6
Uncharacterized protein.
  
 
 0.658
A0A0Q3ETV5
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.636
MED10
Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.611
I1GZS7_BRADI
Uncharacterized protein.
    
 0.604
A0A2K2D0W0
Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.600
Your Current Organism:
Brachypodium distachyon
NCBI taxonomy Id: 15368
Other names: B. distachyon, Brachypodium distachyon (L.) P.Beauv., annual false brome, false brome, purple false brome, stiff brome
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.