STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I1IT89_BRADIDNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (369 aa)    
Predicted Functional Partners:
I1ITK1_BRADI
Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.855
A0A0Q3GDH1
DNA ligase.
  
 
 0.844
A0A2K2DCS7
Uncharacterized protein.
  
 0.807
I1IM16_BRADI
Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
  
 0.807
I1J398_BRADI
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
  
 0.786
I1IAG9_BRADI
ENDO3c domain-containing protein.
  
 0.782
A0A0Q3HUL9
DNA ligase.
  
 
 0.771
A0A2K2DES1
Uncharacterized protein.
  
 0.769
I1HVJ4_BRADI
Small nuclear ribonucleoprotein Sm D2.
   
 0.764
A0A0Q3NY79
Sm domain-containing protein.
   
 0.742
Your Current Organism:
Brachypodium distachyon
NCBI taxonomy Id: 15368
Other names: B. distachyon, Brachypodium distachyon (L.) P.Beauv., annual false brome, false brome, purple false brome, stiff brome
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