STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYP_1449Succinate dehydrogenase cytochrome b subunit, b558 family; Or fumarate reductase. (217 aa)    
Predicted Functional Partners:
MYP_1447
Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
 
 
 0.999
MYP_1448
Succinate dehydrogenase flavoprotein subunit.
 
 
 0.999
sucC
succinyl-CoA synthetase, subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 0.946
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.945
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
     
  0.932
MYP_1867
Iron-sulfur cluster-binding protein, Rieske family.
   
  
 0.674
MYP_4956
Rieske (2Fe-2S) domain-containing protein.
   
  
 0.666
MYP_4742
Cytochrome oxidase subunit III.
   
  
 0.650
MYP_4743
Cytochrome oxidase subunit III.
   
  
 0.650
MYP_618
2-hydroxyhepta-2,4-diene-1,7-dioate isomerase.
    
  0.581
Your Current Organism:
Sporocytophaga myxococcoides
NCBI taxonomy Id: 153721
Other names: ATCC 10010, Cytophaga myxococcoides, DSM 11118, LMG 8393, LMG:8393, S. myxococcoides, Spirochaeta cytophaga
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