STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menDHypothetical protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (561 aa)    
Predicted Functional Partners:
MYP_4671
Hypothetical protein.
 
 
 0.995
MYP_4673
Hypothetical protein.
 
   
 0.877
menB
1,4-dihydroxy-6-naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
  
 0.866
MYP_4670
Esterase.
 
   
 0.849
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
   
 0.838
MYP_787
O-succinylbenzoate synthase.
 
  
 0.838
MYP_3779
Hypothetical protein.
  
 
 0.591
MYP_1093
Hypothetical protein; Belongs to the enoyl-CoA hydratase/isomerase family.
  
   
 0.552
MYP_1460
methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
   
 0.493
MYP_2622
Hypothetical protein Hsw_1047; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
  
 0.466
Your Current Organism:
Sporocytophaga myxococcoides
NCBI taxonomy Id: 153721
Other names: ATCC 10010, Cytophaga myxococcoides, DSM 11118, LMG 8393, LMG:8393, S. myxococcoides, Spirochaeta cytophaga
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