STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AMK76155.1Carbamoyltransferase; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (811 aa)    
Predicted Functional Partners:
AMK76156.1
Hydrogenase expression/formation protein HypE.
 
 
 0.996
AMK76158.1
Hydrogenase formation protein HypD; Belongs to the HypD family.
 
  
 0.909
AMK76159.1
Hydrogenase assembly protein HupF.
 
 
 0.899
hypA
Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.862
AMK76160.1
Hydrogenase nickel incorporation protein HypB.
 
   
 0.831
AMK75589.1
NADP oxidoreductase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
   
 0.721
AMK76174.1
Hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 
 0.695
AMK76175.1
Uptake hydrogenase small subunit.
 
 
 
 0.610
AMK75588.1
NADP oxidoreductase.
 
  
 0.594
AMK76153.1
Toxin YoeB.
       0.584
Your Current Organism:
Methylomonas denitrificans
NCBI taxonomy Id: 1538553
Other names: M. denitrificans, Methylomonas sp. FJG1, strain FJG1
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