STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMK77907.1Topoisomerase II. (75 aa)    
Predicted Functional Partners:
AMK74929.1
Pilus assembly protein PilZ.
  
     0.695
AMK76435.1
Signal transduction protein.
  
     0.652
AMK77918.1
Hypothetical protein.
  
     0.649
AMK75283.1
Pilus assembly protein PilZ; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
  
     0.643
htpX
Zinc metalloprotease HtpX; Belongs to the peptidase M48B family.
       0.631
AMK78859.1
Hypothetical protein.
  
     0.631
AMK77773.1
Hypothetical protein.
  
     0.625
AMK79189.1
Hypothetical protein.
  
     0.590
AMK78846.1
Hypothetical protein.
  
     0.570
AMK77309.1
Cyclic nucleotide-binding protein.
  
     0.569
Your Current Organism:
Methylomonas denitrificans
NCBI taxonomy Id: 1538553
Other names: M. denitrificans, Methylomonas sp. FJG1, strain FJG1
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