STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMK79244.1Methylenetetrahydromethanopterin dehydrogenase. (306 aa)    
Predicted Functional Partners:
AMK77426.1
Aldehyde-activating protein.
  
  
  0.976
AMK77870.1
Aldehyde-activating protein.
  
  
  0.976
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
  
  
  0.976
AMK78616.1
Aldehyde-activating protein.
  
  
  0.976
AMK79240.1
Aldehyde-activating protein.
  
  
  0.976
AMK75556.1
Methylenetetrahydromethanopterin dehydrogenase.
 
 
0.911
AMK75557.1
Methylenetetrahydromethanopterin dehydrogenase.
 
 
0.911
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.906
AMK78660.1
GHMP kinase.
 
     0.780
AMK74964.1
Dihydropteroate synthase.
  
     0.775
Your Current Organism:
Methylomonas denitrificans
NCBI taxonomy Id: 1538553
Other names: M. denitrificans, Methylomonas sp. FJG1, strain FJG1
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