node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADZ25142.1 | ADZ26244.1 | NAL212_0185 | NAL212_1348 | TIGRFAM: Pyruvate kinase; KEGG: nmu:Nmul_A0385 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; Belongs to the pyruvate kinase family. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.916 |
ADZ25142.1 | ADZ27310.1 | NAL212_0185 | NAL212_2505 | TIGRFAM: Pyruvate kinase; KEGG: nmu:Nmul_A0385 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; Belongs to the pyruvate kinase family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.912 |
ADZ25142.1 | ADZ27311.1 | NAL212_0185 | NAL212_2506 | TIGRFAM: Pyruvate kinase; KEGG: nmu:Nmul_A0385 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; Belongs to the pyruvate kinase family. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.907 |
ADZ25142.1 | ADZ27660.1 | NAL212_0185 | NAL212_2874 | TIGRFAM: Pyruvate kinase; KEGG: nmu:Nmul_A0385 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; Belongs to the pyruvate kinase family. | Adenylate/guanylate cyclase with Chase sensor; KEGG: neu:NE1299 guanylate cyclase; PFAM: CHASE2; Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase. | 0.905 |
ADZ25142.1 | gmk | NAL212_0185 | NAL212_1350 | TIGRFAM: Pyruvate kinase; KEGG: nmu:Nmul_A0385 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; Belongs to the pyruvate kinase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.910 |
ADZ25142.1 | ndk | NAL212_0185 | NAL212_1223 | TIGRFAM: Pyruvate kinase; KEGG: nmu:Nmul_A0385 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; Belongs to the pyruvate kinase family. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.907 |
ADZ25142.1 | rplK | NAL212_0185 | NAL212_2144 | TIGRFAM: Pyruvate kinase; KEGG: nmu:Nmul_A0385 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; Belongs to the pyruvate kinase family. | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.919 |
ADZ25142.1 | rpsL | NAL212_0185 | NAL212_1130 | TIGRFAM: Pyruvate kinase; KEGG: nmu:Nmul_A0385 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; Belongs to the pyruvate kinase family. | Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.931 |
ADZ26244.1 | ADZ25142.1 | NAL212_1348 | NAL212_0185 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | TIGRFAM: Pyruvate kinase; KEGG: nmu:Nmul_A0385 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; Belongs to the pyruvate kinase family. | 0.916 |
ADZ26244.1 | ADZ26367.1 | NAL212_1348 | NAL212_1483 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | TIGRFAM: Exopolyphosphatase; KEGG: abo:ABO_2461 hypothetical protein; PFAM: Ppx/GppA phosphatase. | 0.927 |
ADZ26244.1 | ADZ27310.1 | NAL212_1348 | NAL212_2505 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.900 |
ADZ26244.1 | ADZ27311.1 | NAL212_1348 | NAL212_2506 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.911 |
ADZ26244.1 | ADZ27660.1 | NAL212_1348 | NAL212_2874 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Adenylate/guanylate cyclase with Chase sensor; KEGG: neu:NE1299 guanylate cyclase; PFAM: CHASE2; Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase. | 0.900 |
ADZ26244.1 | gmk | NAL212_1348 | NAL212_1350 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.945 |
ADZ26244.1 | ndk | NAL212_1348 | NAL212_1223 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.914 |
ADZ26244.1 | rplK | NAL212_1348 | NAL212_2144 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.875 |
ADZ26244.1 | rpsF | NAL212_1348 | NAL212_0576 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.896 |
ADZ26244.1 | rpsL | NAL212_1348 | NAL212_1130 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.870 |
ADZ26367.1 | ADZ26244.1 | NAL212_1483 | NAL212_1348 | TIGRFAM: Exopolyphosphatase; KEGG: abo:ABO_2461 hypothetical protein; PFAM: Ppx/GppA phosphatase. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.927 |
ADZ27310.1 | ADZ25142.1 | NAL212_2505 | NAL212_0185 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | TIGRFAM: Pyruvate kinase; KEGG: nmu:Nmul_A0385 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; Belongs to the pyruvate kinase family. | 0.912 |