STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA_16-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (324 aa)    
Predicted Functional Partners:
pgi_3
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.991
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 0.921
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.916
fbp
Fructose-bisphosphatase.
     
 0.908
fba_2
fructose-1%2C6-bisphosphate aldolase.
 
 
 0.901
lacC
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
  
  
 0.899
pgi_1
Glucose-6-phosphate isomerase Pgi.
  
 0.895
pgi_2
Glucose-6-phosphate isomerase Pgi; Belongs to the GPI family.
  
 0.895
tkt_2
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.891
pfkA_2
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
  
 
0.886
Your Current Organism:
Hungatella hathewayi
NCBI taxonomy Id: 154046
Other names: CCUG 43506, Clostridium hathewayi, Clostridium hathewayi Steer et al. 2002, DSM 13479, H. hathewayi, Hungatella hathewayi (Steer et al. 2002) Kaur et al. 2014, MTCC 10951
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