STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbsK_6PfkB domain-containing protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (630 aa)    
Predicted Functional Partners:
fruA_1
PTS system fructose subfamily transporter subunit IIC.
  
 
 0.900
hrsA_2
PTS system fructose-specific transporter subunit IIB.
  
 
 0.900
tkt_2
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.894
prs_1
Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family.
   
 0.886
prs_2
Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family.
   
 0.886
guaA_1
GMP synthase.
  
 0.879
guaA_2
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 0.879
guaB_1
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.865
guaB_2
Inosine 5-monophosphate dehydrogenase.
   
 0.865
bglF_3
PTS system beta-glucoside-specific transporter subunit IIABC.
  
 
 0.861
Your Current Organism:
Hungatella hathewayi
NCBI taxonomy Id: 154046
Other names: CCUG 43506, Clostridium hathewayi, Clostridium hathewayi Steer et al. 2002, DSM 13479, H. hathewayi, Hungatella hathewayi (Steer et al. 2002) Kaur et al. 2014, MTCC 10951
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.