STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflB_2Formate C-acetyltransferase glycine radical. (83 aa)    
Predicted Functional Partners:
pflB_1
Formate acetyltransferase.
     0.990
pflA_1
Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
 
  
 0.953
porA_1
Pyruvate ferredoxin/flavodoxin oxidoreductase.
    
 0.934
pflC_3
Pyruvate formate-lyase.
 
 
 0.904
csdA_2
Glycyl-radical enzyme activating protein family; Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).
 
 
 0.894
pflC_1
Pyruvate formate-lyase.
 
  
 0.869
pflC_2
Pyruvate formate-lyase.
 
  
 0.869
hpdA_2
Glycyl-radical enzyme activator family protein.
 
  
 0.868
csdA_1
Radical SAM protein.
 
  
 0.867
pflA1
Pyruvate formate-lyase activating enzyme.
 
  
 0.866
Your Current Organism:
Hungatella hathewayi
NCBI taxonomy Id: 154046
Other names: CCUG 43506, Clostridium hathewayi, Clostridium hathewayi Steer et al. 2002, DSM 13479, H. hathewayi, Hungatella hathewayi (Steer et al. 2002) Kaur et al. 2014, MTCC 10951
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