STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysKCysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (302 aa)    
Predicted Functional Partners:
cysE
Serine acetyltransferase.
 
 0.986
cysS
Cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.922
aruH
Arginine--pyruvate transaminase AruH.
  
 0.921
pepA_1
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 0.839
lysS
Lysine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 
 0.660
adhE
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.497
znuA
High-affinity zinc uptake system binding-protein ZnuA precursor.
       0.437
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.428
ftsH
ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
  
 0.425
nifJ
Pyruvate-flavodoxin oxidoreductase.
  
  
 0.420
Your Current Organism:
Izimaplasma sp. HR1
NCBI taxonomy Id: 1541959
Other names: C. Izimaplasma sp. HR1, Candidatus Izimaplasma sp. HR1, Mollicutes bacterium HR1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.