STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polC_2DNA polymerase III PolC-type. (167 aa)    
Predicted Functional Partners:
dnaX_1
DNA polymerase III subunit tau.
  
 0.920
dnaX_2
DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.920
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.920
dnaE
DNA polymerase III subunit alpha.
    
 0.920
AIO19501.1
DNA polymerase III subunit delta.
    
 0.920
polC_3
DNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
  
 
0.905
AIO18787.1
Hypothetical protein.
       0.642
AIO18779.1
Hypothetical protein.
  
    0.512
pta_2
Phosphate acetyltransferase.
       0.504
buk2_1
Butyrate kinase 2; Belongs to the acetokinase family.
       0.504
Your Current Organism:
Izimaplasma sp. HR1
NCBI taxonomy Id: 1541959
Other names: C. Izimaplasma sp. HR1, Candidatus Izimaplasma sp. HR1, Mollicutes bacterium HR1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.