node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OJG69575.1 | OJG71342.1 | RV11_GL002359 | RV11_GL000357 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.799 |
OJG69575.1 | OJG73057.1 | RV11_GL002359 | RV11_GL001867 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III (xth). | 0.984 |
OJG69575.1 | metK | RV11_GL002359 | RV11_GL002630 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.483 |
OJG69575.1 | mutM | RV11_GL002359 | RV11_GL001217 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.481 |
OJG69575.1 | polA | RV11_GL002359 | RV11_GL001218 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.999 |
OJG71340.1 | OJG71342.1 | RV11_GL000355 | RV11_GL000357 | 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.699 |
OJG71340.1 | OJG73057.1 | RV11_GL000355 | RV11_GL001867 | 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Exodeoxyribonuclease III (xth). | 0.489 |
OJG71340.1 | recX | RV11_GL000355 | RV11_GL000356 | 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Recombination regulator RecX; Modulates RecA activity; Belongs to the RecX family. | 0.831 |
OJG71342.1 | OJG69575.1 | RV11_GL000357 | RV11_GL002359 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.799 |
OJG71342.1 | OJG71340.1 | RV11_GL000357 | RV11_GL000355 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.699 |
OJG71342.1 | OJG71343.1 | RV11_GL000357 | RV11_GL000358 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Hypothetical protein; Belongs to the UPF0374 family. | 0.855 |
OJG71342.1 | OJG73057.1 | RV11_GL000357 | RV11_GL001867 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Exodeoxyribonuclease III (xth). | 0.976 |
OJG71342.1 | metK | RV11_GL000357 | RV11_GL002630 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.548 |
OJG71342.1 | mutM | RV11_GL000357 | RV11_GL001217 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.552 |
OJG71342.1 | nth | RV11_GL000357 | RV11_GL002550 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.765 |
OJG71342.1 | polA | RV11_GL000357 | RV11_GL001218 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.575 |
OJG71342.1 | recX | RV11_GL000357 | RV11_GL000356 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Recombination regulator RecX; Modulates RecA activity; Belongs to the RecX family. | 0.864 |
OJG71342.1 | sfsA | RV11_GL000357 | RV11_GL000903 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Sugar fermentation stimulation protein; Belongs to the SfsA family. | 0.925 |
OJG71343.1 | OJG71342.1 | RV11_GL000358 | RV11_GL000357 | Hypothetical protein; Belongs to the UPF0374 family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.855 |
OJG71343.1 | recX | RV11_GL000358 | RV11_GL000356 | Hypothetical protein; Belongs to the UPF0374 family. | Recombination regulator RecX; Modulates RecA activity; Belongs to the RecX family. | 0.779 |