STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISF6_0054ADP-heptose synthase/D-glycero-beta-D-manno-heptose 7-phosphate kinase. (332 aa)    
Predicted Functional Partners:
hldD
ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
 
 
 0.983
ISF6_1248
Cytidyltransferase-related domain protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
   
 0.982
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
  
 0.974
ISF6_0702
D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Histidinol-phosphatase (EC 3.1.3.15).
 
  
 0.964
ISF6_2862
ADP-heptose--lipooligosaccharide heptosyltransferase II.
 
  
 0.906
ISF6_1847
ADP-heptose--lipooligosaccharide heptosyltransferase II.
 
  
 0.883
ISF6_2504
ADP-heptose--lipooligosaccharide heptosyltransferase II.
 
  
 0.864
ISF6_2659
Lipopolysaccharide heptosyltransferase I.
 
  
 0.848
lapB
Heat shock protein YciM, precursor; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
       0.803
ISF6_0056
Putative transmembrane protein.
       0.803
Your Current Organism:
Ideonella sakaiensis
NCBI taxonomy Id: 1547922
Other names: I. sakaiensis, Ideonella sakaiensis Tanasupawat et al. 2016, Ideonella sp. 201-F6, NBRC 110686, TISTR 2288, strain 201-F6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.