STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
deoAThymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (475 aa)    
Predicted Functional Partners:
ISF6_2088
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.
 
 
 0.982
ISF6_2086
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
 
 0.973
ISF6_5183
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
 
  
 0.855
ISF6_2090
5'-nucleotidase; Belongs to the 5'-nucleotidase family.
    
  0.829
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
 
 0.815
ISF6_2089
Hypothetical protein.
       0.757
tdk
Thymidine kinase.
 
  
 0.751
ISF6_3953
Thymidine phosphorylase.
  
     0.740
ISF6_3930
Thymidine phosphorylase.
  
  
 
0.721
ISF6_4643
Cytosine deaminase.
 
  
 0.689
Your Current Organism:
Ideonella sakaiensis
NCBI taxonomy Id: 1547922
Other names: I. sakaiensis, Ideonella sakaiensis Tanasupawat et al. 2016, Ideonella sp. 201-F6, NBRC 110686, TISTR 2288, strain 201-F6
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