STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISF6_3121Hypothetical protein. (761 aa)    
Predicted Functional Partners:
ISF6_1736
Hypothetical protein.
  
     0.501
ISF6_3120
Hypothetical protein.
       0.465
ISF6_3118
Hypothetical protein.
 
     0.455
ISF6_3114
Beta-glucanase precursor.
 
   
 0.450
ISF6_3117
Putative sugar transporter.
 
     0.447
rpsH
SSU ribosomal protein S8p (S15Ae); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
    
   0.446
ISF6_3119
Beta (1-6) glucans synthase.
       0.443
ISF6_5024
Proline iminopeptidase.
  
 
   0.420
ISF6_4831
Lipase; Involved in the degradation and assimilation of the plastic poly(ethylene terephthalate) (PET), which allows I.sakaiensis to use PET as its major energy and carbon source for growth. Likely acts synergistically with MHETase to depolymerize PET. Catalyzes the hydrolysis of PET to produce mono(2-hydroxyethyl) terephthalate (MHET) as the major product. Also depolymerizes another semiaromatic polyester, poly(ethylene-2,5- furandicarboxylate) (PEF), which is an emerging, bioderived PET replacement with improved gas barrier properties. In contrast, PETase does not degrade aliphatic p [...]
  
     0.416
Your Current Organism:
Ideonella sakaiensis
NCBI taxonomy Id: 1547922
Other names: I. sakaiensis, Ideonella sakaiensis Tanasupawat et al. 2016, Ideonella sp. 201-F6, NBRC 110686, TISTR 2288, strain 201-F6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.