Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CSCA_0260Cystathionine gamma-synthase. (382 aa)    
Predicted Functional Partners:
CSCA_0261
Pyridoxal-5'-phosphate-dependent protein beta subunit.
 
 0.993
CSCA_3858
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.973
CSCA_3667
Homocysteine S-methyltransferase.
  
 
 0.960
luxS
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
 
 0.941
CSCA_1815
O-acetylhomoserine/O-acetylserine sulfhydrylase.
 
 
0.937
CSCA_0240
O-acetylhomoserine/O-acetylserine sulfhydrylase.
 
 
0.933
CSCA_2383
Aminotransferase class I and II.
 
 
 0.933
CSCA_2911
Aminotransferase class I and II.
 
 
 0.933
CSCA_3669
O-acetylhomoserine/O-acetylserine sulfhydrylase.
 
 
0.933
CSCA_1816
Homocysteine S-methyltransferase.
  
 
 0.926
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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