Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CSCA_0446Histidine kinase. (287 aa)    
Predicted Functional Partners:
CSCA_0445
DNA-binding response regulator.
 
 
 0.917
CSCA_0442
ABC transporter, permease.
 
 
 
 0.897
CSCA_0441
ABC transporter related protein.
 
 
 0.873
CSCA_0440
ABC transporter, ATP-binding protein.
 
 
 0.863
CSCA_2213
Protein of unknown function DUF214.
 
 
 
 0.861
CSCA_1899
Two component transcriptional regulator, winged helix family.
 
 
 0.847
CSCA_2217
Two-component response regulator.
 
 
 0.847
CSCA_2277
Two component transcriptional regulator, winged helix family.
 
 
 0.844
CSCA_0938
Two component transcriptional regulator, winged helix family.
 
 
 0.837
CSCA_1027
Transcriptional regulator.
 
 
 0.829
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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