Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CSCA_0573Malic enzyme. (390 aa)    
Predicted Functional Partners:
CSCA_4419
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.965
CSCA_1055
Lactate/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 0.953
CSCA_2965
Lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.953
CSCA_4563
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.947
CSCA_4330
Hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type.
 
 
 0.942
CSCA_3215
Pyruvate:ferredoxin oxidoreductase.
  
 
 0.935
CSCA_1352
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.934
CSCA_4329
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit.
  
 
 0.924
CSCA_2820
Phosphate acetyltransferase.
 
  
 0.916
CSCA_0591
FAD linked oxidase domain protein.
  
 
 0.912
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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