Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CSCA_0760Stage II sporulation protein E (SpoIIE). (390 aa)    
Predicted Functional Partners:
CSCA_0758
Hypothetical protein.
 
    0.961
CSCA_0759
Hydrogenase large subunit domain protein.
 
     0.959
CSCA_1760
Multi-sensor hybrid histidine kinase.
  
  
 0.879
CSCA_5176
STAS domain protein; Belongs to the anti-sigma-factor antagonist family.
  
 
 0.858
CSCA_3574
PAS domain S-box domain-containing protein.
  
  
 0.840
CSCA_1808
Thiamine biosynthesis protein ThiH.
  
    0.793
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.775
CSCA_5174
Putative anti-sigma regulatory factor, serine/threonine protein kinase.
  
 
 0.775
CSCA_3201
Flagellar motor switch protein FliM.
  
    0.715
CSCA_0875
Diguanylate cyclase (GGDEF) domain protein.
 
  
 0.661
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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