Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sigIPutative RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; Belongs to the sigma-70 factor family. SigI subfamily. (228 aa)    
Predicted Functional Partners:
CSCA_1464
Hypothetical protein.
 
 
 0.989
CSCA_3199
Anti-sigma-28 factor, FlgM.
  
 
 0.888
CSCA_3138
Bifunctional flagellar biosynthesis proteins FliR/FlhB; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.
  
  
 0.873
CSCA_3200
CheC, inhibitor of MCP methylation / FliN fusion protein.
  
  
 0.801
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.753
CSCA_5174
Putative anti-sigma regulatory factor, serine/threonine protein kinase.
  
 
 0.753
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.735
CSCA_3155
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
  
 
 0.734
CSCA_3154
Flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family.
  
 
 0.732
CSCA_3197
Flagellar hook-associated protein FlgK; Belongs to the flagella basal body rod proteins family.
  
  
 0.723
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.