Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CSCA_2125HAD-superfamily hydrolase, subfamily IA, variant 1. (233 aa)    
Predicted Functional Partners:
CSCA_2124
Transcriptional regulator, Crp/Fnr family.
 
     0.561
CSCA_3364
FAD dependent oxidoreductase family protein.
 
 
 0.538
CSCA_4226
2-alkenal reductase.
 
 
  0.457
CSCA_3228
Glycerol uptake facilitator; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.441
CSCA_5283
Glycerol uptake facilitator; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.441
CSCA_3500
2-alkenal reductase.
 
 
  0.435
CSCA_2676
Pyridine nucleotide-disulfide oxidoreductase; Belongs to the sulfur carrier protein TusA family.
 
 
 0.427
CSCA_4054
Serine--pyruvate transaminase.
  
 
 0.413
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.412
lon
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
 
  0.405
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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