Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CSCA_2777DHHA1 domain protein. (319 aa)    
Predicted Functional Partners:
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
  
    0.929
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
  
 0.813
CSCA_2775
Riboflavin biosynthesis protein RibF; Belongs to the ribF family.
       0.787
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
    0.779
rny
RNA binding metal dependent phosphohydrolase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
 
   
 0.762
CSCA_2781
Protein of unknown function DUF448.
  
    0.717
nusA
NusA antitermination factor; Participates in both transcription termination and antitermination.
 
     0.674
CSCA_2780
Ribosomal protein L7Ae/L30e/S12e/Gadd45.
       0.663
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
       0.618
rimP
Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
       0.617
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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