| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSCA_1663 | CSCA_3105 | CSCA_1663 | CSCA_3105 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | 3-dehydroquinate synthase. | 0.991 |
| CSCA_1663 | aroA | CSCA_1663 | CSCA_1660 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.951 |
| CSCA_1663 | aroB | CSCA_1663 | CSCA_1661 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.997 |
| CSCA_1663 | aroC | CSCA_1663 | CSCA_1659 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.934 |
| CSCA_1663 | aroE-2 | CSCA_1663 | CSCA_1641 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Hypothetical protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.511 |
| CSCA_1663 | aroE-5 | CSCA_1663 | CSCA_1657 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.884 |
| CSCA_1663 | aroK | CSCA_1663 | CSCA_1656 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.876 |
| CSCA_1663 | aroQ | CSCA_1663 | CSCA_0417 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.561 |
| CSCA_3104 | CSCA_3105 | CSCA_3104 | CSCA_3105 | Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 3-dehydroquinate synthase. | 0.795 |
| CSCA_3104 | aroA | CSCA_3104 | CSCA_1660 | Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.437 |
| CSCA_3105 | CSCA_1663 | CSCA_3105 | CSCA_1663 | 3-dehydroquinate synthase. | Phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.991 |
| CSCA_3105 | CSCA_3104 | CSCA_3105 | CSCA_3104 | 3-dehydroquinate synthase. | Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.795 |
| CSCA_3105 | aroA | CSCA_3105 | CSCA_1660 | 3-dehydroquinate synthase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.982 |
| CSCA_3105 | aroB | CSCA_3105 | CSCA_1661 | 3-dehydroquinate synthase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.919 |
| CSCA_3105 | aroC | CSCA_3105 | CSCA_1659 | 3-dehydroquinate synthase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.949 |
| CSCA_3105 | aroD | CSCA_3105 | CSCA_1652 | 3-dehydroquinate synthase. | 3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.935 |
| CSCA_3105 | aroE-2 | CSCA_3105 | CSCA_1641 | 3-dehydroquinate synthase. | Hypothetical protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.919 |
| CSCA_3105 | aroE-5 | CSCA_3105 | CSCA_1657 | 3-dehydroquinate synthase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.842 |
| CSCA_3105 | aroK | CSCA_3105 | CSCA_1656 | 3-dehydroquinate synthase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.981 |
| CSCA_3105 | aroQ | CSCA_3105 | CSCA_0417 | 3-dehydroquinate synthase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.961 |