Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CSCA_3198FlgN family protein. (136 aa)    
Predicted Functional Partners:
CSCA_3196
Flagellar hook-associated protein 3.
  
    0.953
CSCA_1254
Response regulator receiver modulated CheW protein.
  
    0.917
CSCA_3197
Flagellar hook-associated protein FlgK; Belongs to the flagella basal body rod proteins family.
  
    0.850
CSCA_3199
Anti-sigma-28 factor, FlgM.
       0.810
fliW
Protein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
       0.718
CSCA_3202
CheW protein.
  
    0.668
CSCA_3200
CheC, inhibitor of MCP methylation / FliN fusion protein.
       0.646
CSCA_3188
Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
  
    0.610
csrA
Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
       0.609
CSCA_3201
Flagellar motor switch protein FliM.
       0.580
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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