Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CSCA_3877Branched-chain amino acid aminotransferase. (341 aa)    
Predicted Functional Partners:
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.979
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.970
CSCA_4374
Cystathionine gamma-synthase.
   
 0.918
CSCA_3212
Aminotransferase class IV.
     
  0.900
CSCA_1209
Threonine dehydratase.
  
 0.897
CSCA_4626
Threonine dehydratase.
  
 0.891
CSCA_1208
Homoserine dehydrogenase.
  
 
 0.874
CSCA_3670
Homoserine dehydrogenase.
  
 
 0.874
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.856
CSCA_1055
Lactate/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 0.845
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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