| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSCA_2848 | CSCA_3058 | CSCA_2848 | CSCA_3058 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.858 |
| CSCA_2848 | CSCA_3074 | CSCA_2848 | CSCA_3074 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage III sporulation protein AG. | 0.855 |
| CSCA_2848 | CSCA_3076 | CSCA_2848 | CSCA_3076 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage III sporulation protein AE. | 0.849 |
| CSCA_2848 | CSCA_3078 | CSCA_2848 | CSCA_3078 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage III sporulation protein AC. | 0.854 |
| CSCA_2848 | CSCA_3080 | CSCA_2848 | CSCA_3080 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage III sporulation protein AA. | 0.884 |
| CSCA_2848 | CSCA_3541 | CSCA_2848 | CSCA_3541 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage II sporulation protein P. | 0.869 |
| CSCA_2848 | CSCA_3906 | CSCA_2848 | CSCA_3906 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Sporulation transcriptional regulator SpoIIID. | 0.890 |
| CSCA_2848 | CSCA_3944 | CSCA_2848 | CSCA_3944 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage II sporulation protein R. | 0.844 |
| CSCA_2848 | CSCA_4230 | CSCA_2848 | CSCA_4230 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Transcriptional regulator, AbrB family. | 0.814 |
| CSCA_2848 | spoIIAB | CSCA_2848 | CSCA_4806 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.847 |
| CSCA_3058 | CSCA_2848 | CSCA_3058 | CSCA_2848 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.858 |
| CSCA_3058 | CSCA_3074 | CSCA_3058 | CSCA_3074 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage III sporulation protein AG. | 0.831 |
| CSCA_3058 | CSCA_3076 | CSCA_3058 | CSCA_3076 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage III sporulation protein AE. | 0.824 |
| CSCA_3058 | CSCA_3078 | CSCA_3058 | CSCA_3078 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage III sporulation protein AC. | 0.820 |
| CSCA_3058 | CSCA_3080 | CSCA_3058 | CSCA_3080 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage III sporulation protein AA. | 0.840 |
| CSCA_3058 | CSCA_3541 | CSCA_3058 | CSCA_3541 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage II sporulation protein P. | 0.832 |
| CSCA_3058 | CSCA_3906 | CSCA_3058 | CSCA_3906 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Sporulation transcriptional regulator SpoIIID. | 0.857 |
| CSCA_3058 | CSCA_3944 | CSCA_3058 | CSCA_3944 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage II sporulation protein R. | 0.841 |
| CSCA_3058 | CSCA_4230 | CSCA_3058 | CSCA_4230 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Transcriptional regulator, AbrB family. | 0.839 |
| CSCA_3058 | spoIIAB | CSCA_3058 | CSCA_4806 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.866 |