| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSCA_2848 | CSCA_2866 | CSCA_2848 | CSCA_2866 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Putative sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.806 |
| CSCA_2848 | CSCA_3080 | CSCA_2848 | CSCA_3080 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage III sporulation protein AA. | 0.884 |
| CSCA_2848 | CSCA_3541 | CSCA_2848 | CSCA_3541 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage II sporulation protein P. | 0.869 |
| CSCA_2848 | CSCA_3906 | CSCA_2848 | CSCA_3906 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Sporulation transcriptional regulator SpoIIID. | 0.890 |
| CSCA_2848 | CSCA_3944 | CSCA_2848 | CSCA_3944 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage II sporulation protein R. | 0.844 |
| CSCA_2848 | CSCA_3945 | CSCA_2848 | CSCA_3945 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Germination protein, Ger(x)C family. | 0.506 |
| CSCA_2848 | CSCA_3947 | CSCA_2848 | CSCA_3947 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | GerA spore germination protein. | 0.773 |
| CSCA_2848 | CSCA_4230 | CSCA_2848 | CSCA_4230 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Transcriptional regulator, AbrB family. | 0.814 |
| CSCA_2848 | CSCA_4239 | CSCA_2848 | CSCA_4239 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage II sporulation protein E, protein serine/threonine phosphatase. | 0.832 |
| CSCA_2848 | spoIIAB | CSCA_2848 | CSCA_4806 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.847 |
| CSCA_2866 | CSCA_2848 | CSCA_2866 | CSCA_2848 | Putative sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.806 |
| CSCA_2866 | CSCA_3080 | CSCA_2866 | CSCA_3080 | Putative sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Stage III sporulation protein AA. | 0.786 |
| CSCA_2866 | CSCA_3541 | CSCA_2866 | CSCA_3541 | Putative sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Stage II sporulation protein P. | 0.827 |
| CSCA_2866 | CSCA_3906 | CSCA_2866 | CSCA_3906 | Putative sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Sporulation transcriptional regulator SpoIIID. | 0.802 |
| CSCA_2866 | CSCA_3944 | CSCA_2866 | CSCA_3944 | Putative sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Stage II sporulation protein R. | 0.856 |
| CSCA_2866 | CSCA_3945 | CSCA_2866 | CSCA_3945 | Putative sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Germination protein, Ger(x)C family. | 0.645 |
| CSCA_2866 | CSCA_3947 | CSCA_2866 | CSCA_3947 | Putative sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | GerA spore germination protein. | 0.625 |
| CSCA_2866 | CSCA_4230 | CSCA_2866 | CSCA_4230 | Putative sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Transcriptional regulator, AbrB family. | 0.708 |
| CSCA_2866 | CSCA_4239 | CSCA_2866 | CSCA_4239 | Putative sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Stage II sporulation protein E, protein serine/threonine phosphatase. | 0.951 |
| CSCA_2866 | spoIIAB | CSCA_2866 | CSCA_4806 | Putative sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.864 |
