Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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larCHypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. (408 aa)    
Predicted Functional Partners:
CSCA_3964
1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase.
 
  
 0.976
CSCA_1722
PP-loop domain protein.
  
 0.904
CSCA_0239
PP-loop domain-containing protein.
  
 0.901
CSCA_0186
Hypothetical protein.
 
  
 0.701
CSCA_1172
Hypothetical protein.
 
  
 0.695
CSCA_2486
Hypothetical protein.
 
  
 0.659
CSCA_2067
Hypothetical protein.
 
  
 0.632
CSCA_3566
CbiM protein.
 
    0.583
CSCA_5053
Cobalt transport protein.
 
    0.492
CSCA_1813
4Fe-4S ferredoxin iron-sulfur binding domain protein.
 
    0.476
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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