Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CSCA_3972D-proline reductase (dithiol). (253 aa)    
Predicted Functional Partners:
CSCA_3971
D-proline reductase (dithiol).
   
 0.988
CSCA_3980
D-proline reductase (dithiol).
   
 0.967
CSCA_3986
PrdA domain-containing protein.
   
 0.905
CSCA_3974
D-proline reductase (dithiol).
   
 0.902
CSCA_3973
D-proline reductase, PrdB subunit, selenocysteine-containing.
 
     0.892
CSCA_3975
Hypothetical protein.
 
     0.885
CSCA_3977
Respiratory-chain NADH dehydrogenase domain 51 kDa subunit.
 
   
 0.872
CSCA_3969
Hypothetical protein.
 
     0.868
CSCA_4123
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.865
CSCA_3983
D-proline reductase (dithiol).
   
 0.845
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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