STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CSCA_4545Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (291 aa)    
Predicted Functional Partners:
CSCA_4548
acetyl-CoA synthase corrinoid iron-sulfur protein small subunit.
  
 0.999
CSCA_3667
Homocysteine S-methyltransferase.
 
 
 0.998
CSCA_4549
acetyl-CoA synthase corrinoid iron-sulfur protein large subunit.
 
  
 0.991
CSCA_4550
5-methyltetrahydrofolate corrinoid iron-sulfur protein methyltransferase.
 
 
 0.990
CSCA_4551
CO dehydrogenase/acetyl-CoA synthase complex, beta subunit.
 
  
 0.990
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
  
 0.984
CSCA_4546
Dihydrolipoamide dehydrogenase.
    
 0.980
CSCA_5050
Dihydropteroate synthase DHPS.
 
 
 0.976
CSCA_0288
Methionine synthase.
 
 
 0.970
CSCA_4544
Hypothetical protein.
 
  
 0.969
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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