Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CSCA_4896Aconitate hydratase domain protein. (767 aa)    
Predicted Functional Partners:
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
  
 0.909
CSCA_1055
Lactate/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 0.857
CSCA_1476
Hypothetical protein.
  
 0.857
CSCA_2965
Lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.857
CSCA_1735
Succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 
 0.842
rpmF
Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
   
 0.836
CSCA_2264
TPP-dependent acetoin dehydrogenase beta-subunit.
   
 0.824
rpsB
Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
 0.796
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
  
 0.793
CSCA_3671
Isocitrate dehydrogenase (NAD(+)).
  
 0.793
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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