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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (467 aa)    
Predicted Functional Partners:
CSCA_0870
Gamma-glutamyltransferase.
  
 
 0.939
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.844
CSCA_2041
Aminotransferase class I and II.
   
  0.828
CSCA_2098
Aminotransferase class I and II.
   
  0.828
CSCA_2759
Aminotransferase class I and II.
   
  0.828
CSCA_5151
Aminotransferase class I and II.
   
  0.828
CSCA_0261
Pyridoxal-5'-phosphate-dependent protein beta subunit.
   
  0.827
CSCA_3858
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
  0.827
CSCA_2383
Aminotransferase class I and II.
  
 
  0.813
CSCA_2911
Aminotransferase class I and II.
  
 
  0.813
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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