STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
csdB4-hydroxyphenylacetate decarboxylase large subunit; Decarboxylates phenylacetates with a hydroxyl group in the p- position. Active toward 4-hydroxyphenylacetate and 3,4- dihydroxyphenylacetate, forming 4-methylphenol and 4-methylcatechol respectively. (897 aa)    
Predicted Functional Partners:
csdC
4-hydroxyphenylacetate decarboxylase small subunit; Decarboxylates phenylacetates with a hydroxyl group in the p- position. Active toward 4-hydroxyphenylacetate and 3,4- dihydroxyphenylacetate, forming 4-methylphenol and 4-methylcatechol respectively.
   
 
 0.967
csdA
4-hydroxyphenylacetate decarboxylase activating enzyme; Activation of 4-hydroxyphenylacetate decarboxylase under anaerobic conditions by generation of an organic free radical.
 
  
 0.948
CSCA_1773
Pyruvate formate-lyase-activating enzyme.
 
  
 0.858
CSCA_0865
Glycyl-radical enzyme activating protein family.
 
  
 0.857
CSCA_1996
Glycyl-radical enzyme activating protein family.
 
  
 0.857
cutD
Glycyl-radical enzyme activating protein family; Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).
 
  
 0.857
CSCA_5158
(Formate-C-acetyltransferase)-activating enzyme.
 
  
 0.830
CSCA_5135
Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
 
  
 0.735
buk-3
Butyrate kinase; Belongs to the acetokinase family.
     
 0.674
CSCA_4463
Dehydratase; Belongs to the IlvD/Edd family.
      
 0.636
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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