| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSCA_3182 | CSCA_5061 | CSCA_3182 | CSCA_5061 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | uroporphyrin-III C-methyltransferase. | 0.791 |
| CSCA_3182 | CSCA_5062 | CSCA_3182 | CSCA_5062 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.991 |
| CSCA_3182 | hemA | CSCA_3182 | CSCA_5058 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.987 |
| CSCA_3182 | hemC | CSCA_3182 | CSCA_5060 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.918 |
| CSCA_3182 | hemL | CSCA_3182 | CSCA_5063 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.934 |
| CSCA_5059 | CSCA_5061 | CSCA_5059 | CSCA_5061 | Precorrin-2 dehydrogenase. | uroporphyrin-III C-methyltransferase. | 0.997 |
| CSCA_5059 | CSCA_5062 | CSCA_5059 | CSCA_5062 | Precorrin-2 dehydrogenase. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.763 |
| CSCA_5059 | CSCA_5066 | CSCA_5059 | CSCA_5066 | Precorrin-2 dehydrogenase. | Precorrin-8X methylmutase CbiC/CobH. | 0.561 |
| CSCA_5059 | CSCA_5072 | CSCA_5059 | CSCA_5072 | Precorrin-2 dehydrogenase. | Precorrin-4 C11-methyltransferase. | 0.524 |
| CSCA_5059 | cbiA | CSCA_5059 | CSCA_5064 | Precorrin-2 dehydrogenase. | Cobyrinic acid A,C-diamide synthase CbiA; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.631 |
| CSCA_5059 | cbiD | CSCA_5059 | CSCA_5067 | Precorrin-2 dehydrogenase. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.523 |
| CSCA_5059 | hemA | CSCA_5059 | CSCA_5058 | Precorrin-2 dehydrogenase. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.932 |
| CSCA_5059 | hemC | CSCA_5059 | CSCA_5060 | Precorrin-2 dehydrogenase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.921 |
| CSCA_5059 | hemL | CSCA_5059 | CSCA_5063 | Precorrin-2 dehydrogenase. | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.752 |
| CSCA_5061 | CSCA_3182 | CSCA_5061 | CSCA_3182 | uroporphyrin-III C-methyltransferase. | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.791 |
| CSCA_5061 | CSCA_5059 | CSCA_5061 | CSCA_5059 | uroporphyrin-III C-methyltransferase. | Precorrin-2 dehydrogenase. | 0.997 |
| CSCA_5061 | CSCA_5062 | CSCA_5061 | CSCA_5062 | uroporphyrin-III C-methyltransferase. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.997 |
| CSCA_5061 | CSCA_5066 | CSCA_5061 | CSCA_5066 | uroporphyrin-III C-methyltransferase. | Precorrin-8X methylmutase CbiC/CobH. | 0.828 |
| CSCA_5061 | CSCA_5072 | CSCA_5061 | CSCA_5072 | uroporphyrin-III C-methyltransferase. | Precorrin-4 C11-methyltransferase. | 0.794 |
| CSCA_5061 | cbiA | CSCA_5061 | CSCA_5064 | uroporphyrin-III C-methyltransferase. | Cobyrinic acid A,C-diamide synthase CbiA; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.849 |