Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CSCA_5069Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit. (212 aa)    
Predicted Functional Partners:
CSCA_5070
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit.
 
 0.999
CSCA_5066
Precorrin-8X methylmutase CbiC/CobH.
 
 
 0.998
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.987
CSCA_5073
Cobalamin (vitamin B12) biosynthesis CbiG protein.
 
  
 0.977
CSCA_5071
Precorrin-2 C20-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.
 
  
 0.967
cbiA
Cobyrinic acid A,C-diamide synthase CbiA; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.933
CSCA_5075
Anaerobic cobalt chelatase.
 
  
 0.931
CSCA_0560
Precorrin-6x reductase.
 
  
 0.924
CSCA_5076
Precorrin-6x reductase.
 
  
 0.918
CSCA_5072
Precorrin-4 C11-methyltransferase.
 
  
0.916
Your Current Organism:
Clostridium scatologenes
NCBI taxonomy Id: 1548
Other names: ATCC 25775, Bacillus scatologenes, C. scatologenes, CCUG 9283, Clostridium scatol, DSM 757, NCIB 8855, NCIB:8855, NCTC 12992
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