ANO53046.1 protein (Woeseia oceani) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

ANO53046.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)

Predicted Functional Partners:

ANO50858.1

0.962

ANO50014.1

0.929

ANO52442.1

0.676

ANO50013.1

0.416

ANO50421.1

0.416

ANO52895.1

0.413

Your Current Organism:

Woeseia oceani

NCBI taxonomy Id: 1548547
Other names: ATCC BAA-2615, CICC 10905, W. oceani, Woeseia oceani Du et al. 2016, gamma proteobacterium XK5, strain XK5

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANO50013.1	ANO50014.1	BA177_01155	BA177_01160	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.851
ANO50013.1	ANO52895.1	BA177_01155	BA177_01145	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.552
ANO50013.1	ANO53046.1	BA177_01155	BA177_06235	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.416
ANO50014.1	ANO50013.1	BA177_01160	BA177_01155	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.851
ANO50014.1	ANO52895.1	BA177_01160	BA177_01145	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.514
ANO50014.1	ANO53046.1	BA177_01160	BA177_06235	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.929
ANO50421.1	ANO53046.1	BA177_03645	BA177_06235	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.416
ANO50858.1	ANO53046.1	BA177_06230	BA177_06235	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.962
ANO52442.1	ANO53046.1	BA177_15735	BA177_06235	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.676
ANO52895.1	ANO50013.1	BA177_01145	BA177_01155	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.552
ANO52895.1	ANO50014.1	BA177_01145	BA177_01160	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.514
ANO52895.1	ANO53046.1	BA177_01145	BA177_06235	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.413
ANO53046.1	ANO50013.1	BA177_06235	BA177_01155	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.416
ANO53046.1	ANO50014.1	BA177_06235	BA177_01160	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.929
ANO53046.1	ANO50421.1	BA177_06235	BA177_03645	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.416
ANO53046.1	ANO50858.1	BA177_06235	BA177_06230	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.962
ANO53046.1	ANO52442.1	BA177_06235	BA177_15735	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.676
ANO53046.1	ANO52895.1	BA177_06235	BA177_01145	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.413

Network Stats

number of nodes:

11

number of edges:

51

average node degree:

9.27

avg. local clustering coefficient:

0.933

expected number of edges:

11

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 105

1.49

3.05

9.78e-14

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 50

1.72

3.73

4.41e-12

GO:0019843

rRNA binding

7 of 37

1.75

3.14

3.89e-09

GO:0003723

RNA binding

8 of 97

1.39

2.1

2.51e-08

GO:0003676

Nucleic acid binding

9 of 402

0.82

0.77

4.82e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 56

1.72

4.19

8.44e-15

GO:0044391

Ribosomal subunit

3 of 13

1.83

1.65

0.00035

GO:0015935

Small ribosomal subunit

2 of 6

1.99

1.22

0.0043

GO:0005622

Intracellular anatomical structure

11 of 1243

0.42

0.36

0.00045

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:113

Structural constituent of ribosome

11 of 52

1.8

4.91

4.22e-17

CL:199

Mixed, incl. Small ribosomal subunit, and Ribosomal protein S13-like, H2TH

4 of 7

2.23

2.99

1.06e-06

CL:116

Structural constituent of ribosome

6 of 35

1.7

2.74

6.32e-08

CL:118

Structural constituent of ribosome

4 of 29

1.61

1.66

0.00012

CL:120

Structural constituent of ribosome

3 of 24

1.57

1.13

0.0033

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 53

1.75

4.34

4.66e-15

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

10 of 45

1.82

4.71

2.44e-15

GOCC:0044391

Ribosomal subunit

4 of 24

1.69

1.83

6.46e-05

GOCC:0022625

Cytosolic large ribosomal subunit

2 of 11

1.73

0.82

0.0246

GOCC:0015935

Small ribosomal subunit

2 of 12

1.69

0.8

0.0258

GOCC:0005622

Intracellular

11 of 1277

0.4

0.34

0.0013

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

10 of 56

1.72

4.15

1.34e-14

KW-0687

Ribonucleoprotein

10 of 56

1.72

4.15

1.34e-14

KW-0699

rRNA-binding

7 of 35

1.77

3.4

5.98e-10

KW-0694

RNA-binding

8 of 63

1.57

2.88

3.82e-10

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00316

Ribosomal protein S1-like RNA-binding domain

2 of 5

2.07

0.9

0.0203

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