node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANO51292.1 | ANO51544.1 | BA177_08835 | BA177_10295 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 0.660 |
ANO51292.1 | ANO51996.1 | BA177_08835 | BA177_13010 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family. | 0.700 |
ANO51292.1 | glyA | BA177_08835 | BA177_06305 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.579 |
ANO51292.1 | hisA | BA177_08835 | BA177_09710 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.624 |
ANO51292.1 | hisB | BA177_08835 | BA177_09700 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the histidinol- phosphatase family. | 0.829 |
ANO51292.1 | hisD | BA177_08835 | BA177_09690 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.763 |
ANO51292.1 | hisF | BA177_08835 | BA177_09715 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.711 |
ANO51544.1 | ANO51292.1 | BA177_10295 | BA177_08835 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.660 |
ANO51544.1 | ANO51626.1 | BA177_10295 | BA177_10805 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.768 |
ANO51544.1 | ANO51996.1 | BA177_10295 | BA177_13010 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family. | 0.773 |
ANO51544.1 | glyA | BA177_10295 | BA177_06305 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.641 |
ANO51544.1 | hisA | BA177_10295 | BA177_09710 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.777 |
ANO51544.1 | hisB | BA177_10295 | BA177_09700 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the histidinol- phosphatase family. | 0.951 |
ANO51544.1 | hisD | BA177_10295 | BA177_09690 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.668 |
ANO51544.1 | hisF | BA177_10295 | BA177_09715 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.880 |
ANO51544.1 | hisH | BA177_10295 | BA177_09705 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.797 |
ANO51544.1 | plsB | BA177_10295 | BA177_14895 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Glycerol-3-phosphate 1-O-acyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the GPAT/DAPAT family. | 0.696 |
ANO51626.1 | ANO51544.1 | BA177_10805 | BA177_10295 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 0.768 |
ANO51996.1 | ANO51292.1 | BA177_13010 | BA177_08835 | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family. | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.700 |
ANO51996.1 | ANO51544.1 | BA177_13010 | BA177_10295 | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 0.773 |